Ever. Just don't do it.
I head to a client's site. In order to connect to their domain I have to let a sysAdmin f*ck with my machine.
Alarm bells go off, but I let the monkey have his banana.
To cut a long story short: it's the next day, many hours of work have been lost. Much frustration has been achieved. And I have a new rule:
No f*cking sys admin is touching this machine, ever.
It's the thin edge of the wedge. We let sysAdmin's screw with our machines today. What's next? Database administrators messing with our databases?